SCHEMBL20155222

SCHEMBL20155222

Cc1cc(O)c(C2CC(O)CC(CO)O2)cc1Cc1ccc2c(c1)CC2

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 20/20 0.64
SLC5A2 P31639 19/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20155248 0.88 SLC5A2 (0.50) SLC5A1SLC5A2
SCHEMBL20154931 0.88 SLC5A2 (0.64) SLC5A1SLC5A2
SCHEMBL20155549 0.87 SLC5A2 (0.66) SLC5A1SLC5A2
SCHEMBL20154885 0.86 SLC5A1 (0.48) SLC5A1SLC5A2
SCHEMBL20154909 0.86 SLC5A2 (0.48) SLC5A1SLC5A2
SCHEMBL20154929 0.84 SLC5A1 (0.53) SLC5A1SLC5A2
SCHEMBL20155206 0.82 SLC5A1 (0.58) SLC5A1SLC5A2
SCHEMBL20154934 0.82 SLC5A2 (0.48) SLC5A1SLC5A2
SCHEMBL20155221 0.82 SLC5A2 (0.45) SLC5A1SLC5A2
SCHEMBL20155213 0.81 SLC5A2 (0.53) SLC5A1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018089449-A1 BENZOCYCLOBUTANE DERIVATIVES USEFUL AS DUAL SGLT1/SGLT2 MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2018-05-17 WO disclosed