Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 20/20 | 0.65 |
| ▸ | SLC5A2 | P31639 | 20/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20155549 | 0.90 | SLC5A2 (0.66) | SLC5A1SLC5A2 | |
| SCHEMBL20155183 | 0.90 | SLC5A2 (0.53) | SLC5A1SLC5A2 | |
| SCHEMBL20154869 | 0.90 | SLC5A2 (0.53) | SLC5A1SLC5A2 | |
| SCHEMBL20155244 | 0.89 | SLC5A2 (0.65) | SLC5A1SLC5A2 | |
| SCHEMBL20155213 | 0.87 | SLC5A2 (0.53) | SLC5A1SLC5A2 | |
| SCHEMBL20154887 | 0.87 | SLC5A2 (0.52) | SLC5A1SLC5A2CYP3A4 | |
| SCHEMBL20155223 | 0.86 | SLC5A2 (0.51) | SLC5A1SLC5A2CYP3A4 | |
| SCHEMBL20155216 | 0.84 | SLC5A1 (0.55) | SLC5A1SLC5A2CYP3A4 | |
| SCHEMBL20154892 | 0.80 | SLC5A1 (0.43) | SLC5A1SLC5A2CYP3A4 | |
| SCHEMBL20154929 | 0.80 | SLC5A1 (0.53) | SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089449-A1 | BENZOCYCLOBUTANE DERIVATIVES USEFUL AS DUAL SGLT1/SGLT2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-17 | — | — | WO | disclosed |