Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140137 | 0.88 | SLC5A1 (0.69) | SLC5A1SLC5A2 | |
| SCHEMBL20155233 | 0.85 | SLC5A2 (0.60) | SLC5A1SLC5A2 | |
| SCHEMBL20140104 | 0.83 | SLC5A2 (1.00) | SLC5A1SLC5A2 | |
| SCHEMBL20154937 | 0.82 | SLC5A2 (0.68) | SLC5A1SLC5A2 | |
| SCHEMBL23700126 | 0.78 | SLC5A2 (0.82) | SLC5A1SLC5A2 | |
| SCHEMBL23700132 | 0.77 | SLC5A2 (0.81) | SLC5A1SLC5A2 | |
| SCHEMBL23700095 | 0.77 | SLC5A2 (0.68) | SLC5A1SLC5A2 | |
| SCHEMBL20155549 | 0.76 | SLC5A2 (0.66) | SLC5A1SLC5A2 | |
| SCHEMBL23700135 | 0.76 | SLC5A2 (0.78) | SLC5A1SLC5A2 | |
| SCHEMBL21562222 | 0.75 | SLC5A2 (1.00) | SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10815210-B2 | Benzocyclobutane derivatives useful as dual SGLT1 / SGLT2 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-10-27 | — | — | US | disclosed |
| US-10815210-B2 | Benzocyclobutane derivatives useful as dual SGLT1 / SGLT2 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2020-10-27 | — | — | US | disclosed |
| WO-2018089449-A1 | BENZOCYCLOBUTANE DERIVATIVES USEFUL AS DUAL SGLT1/SGLT2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10815210-B2 | Benzocyclobutane derivatives useful as dual SGLT1 / SGLT2 modulators | SLC5A2, SLC5A1, SLC2A2 | SLC5A1 2/4885SLC5A2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.