SCHEMBL20155255

SCHEMBL20155255

Cn1cc(-c2cc(N)ccc2Oc2ccc(F)cc2F)c2c(ccn2C)c1=O

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19930712 0.87 BRD4 (0.68) BRD4
SCHEMBL20154915 0.84 BRD4 (0.44) BRD4
SCHEMBL21652770 0.83 BRD4 (0.48) BRD4
SCHEMBL20155366 0.83 BRD4 (0.51) BRD4
SCHEMBL20155708 0.82 BRD4 (0.51) BRD4
SCHEMBL16650778 0.82 BRD4 (0.56) BRD4
SCHEMBL22859377 0.82 BRD4 (0.73) BRD4
SCHEMBL29669812 0.82 BRD4 (0.73) BRD4
SCHEMBL19931128 0.81 BRD4 (0.55) BRD4
SCHEMBL20154973 0.81 BRD4 (0.53) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018086604-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND APPLICATIONS THEREOF 山东罗欣药业集团股份有限公司 2018-05-17 WO disclosed