⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20230871 | 0.82 | HTR2A (0.37) | — | |
| SCHEMBL20093302 | 0.78 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL25118500 | 0.78 | HTR2A (0.37) | — | |
| SCHEMBL19954911 | 0.78 | HTR2A (0.38) | — | |
| SCHEMBL22825592 | 0.71 | CYP1A2 (0.50) | — | |
| SCHEMBL20155649 | 0.69 | HTR2A (0.41) | — | |
| SCHEMBL20098087 | 0.68 | NPSR1 (0.32) | — | |
| SCHEMBL21250494 | 0.65 | TRPV1 (0.36) | — | |
| SCHEMBL29805014 | 0.64 | CNR2 (0.32) | — | |
| SCHEMBL23841158 | 0.64 | HTR2A (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647713-B2 | TYK2 inhibitors and uses thereof | NIMBUS LAKSHMI, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20180134700-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-17 | — | — | US | disclosed |