SCHEMBL20156499

SCHEMBL20156499

CCc1ccc(C(=O)N2CCC(F)(c3ccc(C#N)cc3)CC2)cc1N

nearest known ligand 0.60

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23367536 0.85 FASN (0.65) FASN
SCHEMBL12489387 0.82 FASN (0.60) FASN
SCHEMBL12489066 0.82 FASN (0.66) FASN
SCHEMBL23367719 0.80 FASN (0.50) FASN
SCHEMBL12487926 0.80 FASN (0.58) FASN
SCHEMBL30280945 0.80 FASN (0.58) FASN
SCHEMBL12489526 0.79 FASN (0.75) FASN
SCHEMBL20156376 0.79 FASN (0.72) FASN
SCHEMBL4177247 0.78 FASN (0.59) FASN
SCHEMBL13276980 0.78 FASN (0.60) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018089904-A1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS 3-V BIOSCIENCES, INC. (US) 2018-05-17 WO disclosed