Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.41 |
| ▸ | NRP1 | O14786 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30317451 | 1.00 | TSHR (0.58) | TSHRKDM4EHSD17B10HPGDCA12 | |
| SCHEMBL17923420 | 0.81 | CA12 (0.50) | TSHRKDM4EHSD17B10HPGDCA12 | |
| SCHEMBL7528112 | 0.81 | KDM4E (0.58) | TSHRKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL2122821 | 0.81 | TSHR (0.58) | TSHRKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL27875640 | 0.81 | KDM4E (0.58) | TSHRKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL7521970 | 0.79 | KDM4E (0.61) | TSHRKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL28294998 | 0.79 | CA12 (0.65) | TSHRHSD17B10CA12CA3CA4 | |
| SCHEMBL3568604 | 0.78 | TSHR (0.56) | TSHRKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL30528606 | 0.78 | TSHR (0.56) | TSHRKDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL7522731 | 0.78 | KDM4E (0.54) | TSHRKDM4EHSD17B10HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960032-A | Aryloxy propanol amine beta-adrenaline receptor ligand with beta-arrestin biased agonistic activity and application thereof | 复旦大学 | 2023-04-14 | — | — | CN | disclosed |
| EP-3805218-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | Syros Pharmaceuticals, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |