Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 9/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.44 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140218 | 1.00 | CHRM4 (0.50) | CHRM4MTORRPTORMLST8GRM1 | |
| SCHEMBL20140668 | 0.93 | CHRM4 (0.51) | CHRM4MTORRPTORMLST8GRM1 | |
| SCHEMBL20156969 | 0.93 | CHRM4 (0.51) | CHRM4MTORRPTORMLST8GRM1 | |
| SCHEMBL20157251 | 0.86 | PARP1 (0.49) | MTORRPTORMLST8PARP1 | |
| SCHEMBL20140046 | 0.86 | MTOR (0.47) | CHRM4MTORRPTORMLST8GRM1 | |
| SCHEMBL20140070 | 0.86 | MTOR (0.47) | CHRM4MTORRPTORMLST8GRM1 | |
| SCHEMBL20140048 | 0.86 | MTOR (0.47) | CHRM4MTORRPTORMLST8GRM1 | |
| SCHEMBL20142107 | 0.83 | GRM1 (0.47) | CHRM4MTORRPTORMLST8GRM1 | |
| SCHEMBL20156876 | 0.82 | MTOR (0.44) | CHRM4MTORRPTORMLST8GRM1 | |
| SCHEMBL20156877 | 0.82 | MTOR (0.44) | CHRM4MTORRPTORMLST8GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |