Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.48 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.48 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156981 | 0.85 | MTOR (0.58) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20139960 | 0.84 | MTOR (0.56) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20140631 | 0.84 | MTOR (0.56) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20141188 | 0.82 | MTOR (0.56) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20140642 | 0.79 | MTOR (0.51) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20140541 | 0.77 | MTOR (0.46) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20140760 | 0.77 | MTOR (0.53) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20139883 | 0.77 | MTOR (0.54) | MTORRPTORMLST8ALDH1A1PARP1 | |
| SCHEMBL20156824 | 0.77 | MTOR (0.56) | MTORRPTORMLST8ALDH1A1TACR3 | |
| SCHEMBL20139928 | 0.77 | MTOR (0.56) | MTORRPTORMLST8ALDH1A1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |