Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 8/20 | 0.49 |
| ▸ | RPTOR | Q8N122 | 8/20 | 0.49 |
| ▸ | MLST8 | Q9BVC4 | 8/20 | 0.49 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140200 | 0.89 | MTOR (0.59) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20157274 | 0.89 | MTOR (0.49) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20156964 | 0.87 | MTOR (0.49) | MTORRPTORMLST8KDM4EPARP1 | |
| SCHEMBL20156928 | 0.86 | MTOR (0.49) | MTORRPTORMLST8SLC6A7ALDH1A1 | |
| SCHEMBL20140417 | 0.86 | MTOR (0.51) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20156994 | 0.86 | KDM4E (0.54) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20140323 | 0.86 | KDM4E (0.54) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20140545 | 0.86 | MTOR (0.51) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20156918 | 0.86 | MTOR (0.55) | MTORRPTORMLST8ALDH1A1KDM4E | |
| SCHEMBL20139962 | 0.86 | MTOR (0.55) | MTORRPTORMLST8ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |