Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 6/20 | 0.40 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140345 | 0.88 | MTOR (0.49) | HTR1DHTR1AMTORRPTORMLST8 | |
| SCHEMBL20141682 | 0.79 | AVPR1A (0.49) | HTR1DHTR1AMTORRPTORMLST8 | |
| SCHEMBL20140200 | 0.78 | MTOR (0.59) | MTORRPTORMLST8PARP1TACR3 | |
| SCHEMBL20141003 | 0.77 | MTOR (0.54) | MTORRPTORMLST8PARP1HTT | |
| SCHEMBL20140926 | 0.77 | MTOR (0.54) | MTORRPTORMLST8PARP1HTT | |
| SCHEMBL20140889 | 0.77 | MTOR (0.49) | HTR1DHTR1AMTORRPTORMLST8 | |
| SCHEMBL20140719 | 0.75 | MTOR (0.57) | MTORRPTORMLST8PARP1HTT | |
| SCHEMBL20140246 | 0.75 | MTOR (0.57) | MTORRPTORMLST8PARP1HTT | |
| SCHEMBL20140728 | 0.75 | MTOR (0.46) | MTORRPTORMLST8PARP1HTR2A | |
| SCHEMBL20141543 | 0.75 | MTOR (0.54) | MTORRPTORMLST8PARP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |