Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.39 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.39 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20157222 | 0.87 | GRIN2B (0.38) | GRIN2BKMT2ATET3FBXL19CXXC5 | |
| SCHEMBL20157540 | 0.77 | PLA2G1B (0.38) | GRIN2BKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20157307 | 0.77 | PLA2G1B (0.38) | GRIN2BKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20157298 | 0.77 | PLA2G1B (0.38) | GRIN2BKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20140799 | 0.75 | MTOR (0.49) | ALDH1A1KDM4ECNR1LMNA | |
| SCHEMBL20157000 | 0.72 | MEN1 (0.41) | GRIN2BKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20157353 | 0.70 | MEN1 (0.47) | GRIN2BKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20157210 | 0.70 | KDM4E (0.43) | KMT2AALDH1A1KDM4EMEN1HTT | |
| SCHEMBL20157338 | 0.70 | POLB (0.33) | GRIN2BKMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20157195 | 0.69 | GRIN2B (0.39) | GRIN2BKMT2AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |