Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156884 | 0.95 | CYP1A2 (0.34) | SMN1; SMN2CYP1A2CYP2D6MAPK1POLB | |
| SCHEMBL20157338 | 0.90 | POLB (0.33) | SMN1; SMN2CYP1A2CYP2D6MAPK1POLB | |
| SCHEMBL20157313 | 0.90 | CYP1A2 (0.32) | CYP1A2CYP2D6MAPK1POLBPLA2G1B | |
| SCHEMBL20157224 | 0.89 | CYP1A2 (0.31) | CYP1A2CYP2D6MAPK1POLBPLA2G1B | |
| SCHEMBL20157030 | 0.89 | CYP1A2 (0.31) | SMN1; SMN2CYP1A2CYP2D6MAPK1POLB | |
| SCHEMBL20157536 | 0.88 | CYP1A2 (0.31) | CYP1A2CYP2D6MAPK1POLBPLA2G1B | |
| SCHEMBL20157544 | 0.88 | CYP1A2 (0.31) | CYP1A2CYP2D6MAPK1POLBPLA2G1B | |
| SCHEMBL20157299 | 0.88 | CYP1A2 (0.31) | CYP1A2CYP2D6MAPK1POLBPLA2G1B | |
| SCHEMBL20157072 | 0.88 | CYP1A2 (0.31) | CYP1A2CYP2D6MAPK1POLBPLA2G1B | |
| SCHEMBL20157538 | 0.87 | CYP1A2 (0.30) | CYP1A2CYP2D6MAPK1POLBPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |