Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21362632 | 1.00 | MAP2K1 (0.30) | MAP2K1 | |
| SCHEMBL20157510 | 0.84 | — | — | |
| SCHEMBL21351944 | 0.82 | — | — | |
| SCHEMBL28463911 | 0.79 | — | — | |
| SCHEMBL28463908 | 0.79 | — | — | |
| SCHEMBL28463909 | 0.79 | — | — | |
| SCHEMBL21362270 | 0.76 | — | — | |
| SCHEMBL20157391 | 0.76 | — | — | |
| SCHEMBL20157846 | 0.76 | — | — | |
| SCHEMBL20158138 | 0.75 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086605-A1 | NITROGENOUS MACROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 山东罗欣药业集团股份有限公司 | 2018-05-17 | — | — | WO | disclosed |