Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | IAPP | P10997 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20158615 | 0.92 | FOLH1 (0.40) | FOLH1MCL1ALOX5NFKB1POLB | |
| SCHEMBL18292001 | 0.91 | FOLH1 (0.54) | FOLH1THRATHRBFFAR4FFAR1 | |
| SCHEMBL25741228 | 0.89 | FOLH1 (0.45) | FOLH1THRATHRBFFAR4FFAR1 | |
| SCHEMBL26763509 | 0.82 | FOLH1 (0.46) | FOLH1THRATHRBFFAR1ALOX5 | |
| SCHEMBL1404313 | 0.82 | FOLH1 (0.56) | FOLH1FFAR4FFAR1 | |
| SCHEMBL22571849 | 0.81 | FOLH1 (0.51) | FOLH1THRATHRBFFAR4FFAR1 | |
| SCHEMBL25801389 | 0.81 | FOLH1 (0.52) | FOLH1THRATHRBFFAR4FFAR1 | |
| SCHEMBL27303602 | 0.79 | FOLH1 (0.52) | FOLH1THRATHRBFFAR4TP53 | |
| SCHEMBL25741233 | 0.79 | FOLH1 (0.52) | FOLH1FFAR4FFAR1NFKB1POLB | |
| SCHEMBL18811743 | 0.78 | FOLH1 (0.56) | FOLH1THRATHRBFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180133348-A1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133348-A1 | NUCLEAR IMAGING AND RADIOTHERAPEUTICS AGENTS TARGETING CARBONIC ANHYDRASE IX AND USES THEREOF | CA9, CA14, CA13 | FOLH1 15/4885THRA 1676/4885THRB 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.