Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.73 |
| ▸ | RPTOR | Q8N122 | 5/20 | 0.73 |
| ▸ | MLST8 | Q9BVC4 | 5/20 | 0.73 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL20142195 | 0.95 | MTOR (0.67) | MTORRPTORMLST8CHRM4CHRM2 | |
| SCHEMBL20141139 | 0.93 | MTOR (0.72) | MTORRPTORMLST8CHRM4CHRM2 | |
| SCHEMBL20141137 | 0.93 | MTOR (0.72) | MTORRPTORMLST8CHRM4CHRM2 | |
| SCHEMBL20141653 | 0.93 | MTOR (0.71) | MTORRPTORMLST8CHRM4MGLL | |
| SCHEMBL20141650 | 0.93 | MTOR (0.71) | MTORRPTORMLST8CHRM4MGLL | |
| SCHEMBL20159012 | 0.92 | MTOR (0.72) | MTORRPTORMLST8CHRM4CHRM2 | |
| SCHEMBL20139219 | 0.90 | MTOR (0.73) | MTORRPTORMLST8CHRM4CHRM2 | |
| SCHEMBL20139220 | 0.90 | MTOR (0.73) | MTORRPTORMLST8CHRM4CHRM2 | |
| SCHEMBL20142216 | 0.89 | MTOR (0.74) | MTORRPTORMLST8CHRM4CHRM2 | |
| SCHEMBL20142217 | 0.89 | MTOR (0.74) | MTORRPTORMLST8CHRM4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089493-A1 | PYRROLE mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |