Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20159186 | 1.00 | NAMPT (0.44) | NAMPT | |
| SCHEMBL20159197 | 1.00 | NAMPT (0.44) | NAMPT | |
| SCHEMBL20159540 | 0.87 | NAMPT (0.38) | NAMPT | |
| SCHEMBL20138884 | 0.87 | NAMPT (0.38) | NAMPT | |
| SCHEMBL20142989 | 0.87 | NAMPT (0.38) | NAMPT | |
| SCHEMBL20159185 | 0.85 | NAMPT (0.46) | NAMPT | |
| SCHEMBL20159436 | 0.85 | HDAC1 (0.37) | NAMPT | |
| SCHEMBL20159183 | 0.83 | NAMPT (0.61) | NAMPT | |
| SCHEMBL20159180 | 0.83 | NAMPT (0.61) | NAMPT | |
| SCHEMBL20159181 | 0.83 | NAMPT (0.61) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086703-A1 | DIHYDROPYRIDAZINONES SUBSTITUTED WITH PHENYLUREAS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |