Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31413498 | 1.00 | HTR2A (0.49) | HTR2ATRPM8TAAR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL31413396 | 0.98 | HTR2A (0.47) | HTR2ATRPM8TAAR1KDM4EALDH1A1 | |
| SCHEMBL2018112 | 0.83 | HTR2A (0.49) | HTR2ATRPM8TAAR1KDM4EALDH1A1 | |
| SCHEMBL423154 | 0.82 | CYP2A6 (0.46) | HTR2ATRPM8TAAR1KDM4EALDH1A1 | |
| SCHEMBL4513207 | 0.81 | SKP2 (0.40) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL6264119 | 0.81 | KDM4E (0.42) | HTR2ATRPM8KDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL933206 | 0.80 | CYP2A6 (0.44) | HTR2ATRPM8TAAR1KDM4EALDH1A1 | |
| SCHEMBL18469203 | 0.79 | TAAR1 (0.40) | TAAR1KDM4EALDH1A1MEN1KMT2A | |
| Bromide SCHEMBL7930547 | 0.79 | KDM4E (0.41) | HTR2ATRPM8KDM4EALDH1A1MEN1 | |
| SCHEMBL5041752 | 0.78 | TAAR1 (0.50) | HTR2ATRPM8TAAR1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079087-A1 | ENAC BLOCKERS | GLAXO GROUP LIMITED (GB) | 2011-06-30 | — | — | WO | disclosed |