Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 6/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | DCK | P27707 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18971488 | 0.81 | CYP2C19 (0.47) | CYP2C19DPP4DPP8DPP7LRRK2 | |
| SCHEMBL21374619 | 0.81 | CYP2C19 (0.52) | CYP2C19DPP4DPP8DPP7LRRK2 | |
| SCHEMBL18971147 | 0.81 | CYP2C19 (0.52) | CYP2C19DPP4DPP8DPP7LRRK2 | |
| SCHEMBL18952491 | 0.81 | CYP2C19 (0.52) | CYP2C19DPP4DPP8DPP7LRRK2 | |
| SCHEMBL18952489 | 0.81 | CYP2C19 (0.52) | CYP2C19DPP4DPP8DPP7LRRK2 | |
| SCHEMBL21050488 | 0.81 | CYP2C19 (0.52) | CYP2C19DPP4DPP8DPP7LRRK2 | |
| SCHEMBL23504776 | 0.81 | HRH3 (0.40) | DPP4DPP8DPP7CYP17A1PSEN1 | |
| SCHEMBL22638877 | 0.75 | CYP2C19 (0.55) | CYP2C19DPP4DPP8DPP7LRRK2 | |
| SCHEMBL2275882 | 0.75 | CYP2C19 (0.63) | CYP2C19CYP17A1DCKRIPK1ELOVL1 | |
| Hydrochloric Acid SCHEMBL17077948 | 0.74 | CYP2C19 (0.61) | CYP2C19CYP17A1DCKRIPK1ELOVL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087018-A1 | PHENOXYTRIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-05-17 | — | — | WO | disclosed |