⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22166556 | 0.78 | — | — | |
| SCHEMBL19988320 | 0.76 | — | — | |
| SCHEMBL27938072 | 0.74 | — | — | |
| SCHEMBL19074556 | 0.72 | — | — | |
| SCHEMBL24816824 | 0.70 | — | — | |
| SCHEMBL21725810 | 0.70 | — | — | |
| SCHEMBL24003166 | 0.70 | — | — | |
| SCHEMBL17529424 | 0.69 | — | — | |
| SCHEMBL27638600 | 0.69 | — | — | |
| SCHEMBL13939811 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| US-10696700-B2 | Charged linkers and their uses for conjugation | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-06-30 | — | — | US | disclosed |
| US-10696699-B2 | Charged linkers and their uses for conjugation | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-06-30 | — | — | US | disclosed |
| US-10683314-B2 | Charged linkers and their uses for conjugation | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-06-16 | — | — | US | disclosed |
| US-20190127399-A1 | CHARGED LINKERS AND THEIR USES FOR CONJUGATION | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2019-05-02 | — | — | US | disclosed |
| WO-2018086139-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2018-05-17 | — | — | WO | disclosed |