Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20138608 | 0.88 | MME (0.39) | MMEACECPA1ACE2 | |
| SCHEMBL20529494 | 0.88 | MME (0.39) | MMEACECPA1ACE2 | |
| SCHEMBL31743251 | 0.88 | MME (0.39) | MMEACECPA1ACE2 | |
| SCHEMBL24117928 | 0.82 | MME (0.35) | MMEACECPA1ACE2 | |
| SCHEMBL21787951 | 0.79 | MME (0.39) | MMEACECPA1ACE2 | |
| SCHEMBL1081350 | 0.73 | TSHR (0.62) | TSHRMMEACECPA1ACE2 | |
| SCHEMBL1647678 | 0.73 | TSHR (0.62) | TSHRMMEACECPA1ACE2 | |
| SCHEMBL15226591 | 0.73 | TSHR (0.62) | TSHRMMEACECPA1ACE2 | |
| SCHEMBL29951883 | 0.73 | MME (0.38) | TSHRMMEACECPA1ACE2 | |
| SCHEMBL20160181 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018086139-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2018-05-17 | — | — | WO | disclosed |