Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13160479 | 0.83 | TSHR (0.37) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL16327271 | 0.83 | TSHR (0.37) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1699613 | 0.83 | TSHR (0.37) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL19155801 | 0.83 | TSHR (0.42) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL23979426 | 0.82 | TSHR (0.39) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL18386364 | 0.82 | TSHR (0.39) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL19771570 | 0.82 | TSHR (0.39) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL26841703 | 0.81 | TSHR (0.38) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL11921515 | 0.81 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL16489120 | 0.81 | TSHR (0.54) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10784455-B2 | Coatings for barrier films and methods of making and using the same | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-09-22 | — | — | US | disclosed |
| US-20180138433-A1 | COATINGS FOR BARRIER FILMS AND METHODS OF MAKING AND USING THE SAME | 3M INNOVATIVE PROPERTIES CO (US) | 2018-05-17 | — | — | US | disclosed |