Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.60 |
| ▸ | GSK3A | P49840 | 1/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18208874 | 0.99 | GSK3B (0.59) | GSK3BGSK3AHDAC3HDAC1HDAC2 | |
| SCHEMBL18216169 | 0.86 | GSK3B (0.61) | GSK3BGSK3AKMT2AMAPTTSHR | |
| Hydrochloric Acid SCHEMBL18208234 | 0.85 | GSK3B (0.60) | GSK3BGSK3AKMT2AMAPT | |
| SCHEMBL30785575 | 0.84 | GAA (0.55) | GSK3BHDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL18208167 | 0.82 | GSK3B (0.58) | GSK3BGSK3AKMT2AMAPT | |
| SCHEMBL18208170 | 0.82 | GSK3B (0.58) | GSK3BGSK3AKMT2AMAPT | |
| SCHEMBL16568954 | 0.79 | KMT2A (0.54) | GSK3BHDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL29856319 | 0.78 | MAPT (0.62) | GSK3BHDAC3HDAC1HDAC2KMT2A | |
| SCHEMBL20138846 | 0.76 | GSK3A (0.56) | GSK3BGSK3AGRM4KMT2AMAPT | |
| SCHEMBL20138847 | 0.76 | GSK3A (0.56) | GSK3BGSK3AGRM4KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018087126-A1 | AMIDO-SUBSTITUTED CYCLOHEXANE DERIVATIVES AS INHIBITORS OF TANKYRASE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-05-17 | — | — | WO | disclosed |