Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140188 | 0.87 | TLR7 (0.30) | — | |
| SCHEMBL21564215 | 0.84 | HIF1A (0.41) | — | |
| SCHEMBL20161157 | 0.75 | CACNA1B (0.32) | — | |
| SCHEMBL20140274 | 0.75 | PDE4A (0.33) | — | |
| SCHEMBL20161158 | 0.74 | HIF1A (0.41) | — | |
| SCHEMBL20140185 | 0.72 | — | — | |
| SCHEMBL20148884 | 0.72 | HIF1A (0.38) | — | |
| SCHEMBL24205854 | 0.69 | PDE5A (0.37) | — | |
| SCHEMBL20161104 | 0.67 | PRMT5 (0.30) | PRMT5WDR77 | |
| SCHEMBL20161288 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089330-A2 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |