Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 18/20 | 0.61 |
| ▸ | BTK | Q06187 | 17/20 | 0.61 |
| ▸ | TXK | P42681 | 15/20 | 0.54 |
| ▸ | ITK | Q08881 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161769 | 0.88 | JAK3 (0.67) | JAK3BTKTXKITK | |
| SCHEMBL20162006 | 0.88 | JAK3 (0.62) | JAK3BTKTXKITK | |
| SCHEMBL14460569 | 0.82 | ITK (0.70) | JAK3BTKTXKITK | |
| SCHEMBL30291400 | 0.82 | ITK (0.70) | JAK3BTKTXKITK | |
| SCHEMBL25876456 | 0.81 | ITK (0.61) | JAK3BTKTXKITK | |
| SCHEMBL14460588 | 0.79 | ITK (0.60) | JAK3BTKTXKITK | |
| SCHEMBL20161432 | 0.79 | ITK (0.62) | JAK3BTKTXKITK | |
| SCHEMBL24467265 | 0.78 | JAK3 (0.83) | JAK3BTKTXKITK | |
| SCHEMBL14461105 | 0.78 | JAK3 (0.63) | JAK3BTKTXKITK | |
| SCHEMBL24467329 | 0.78 | JAK3 (0.68) | JAK3BTKTXKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |