⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23134363 | 0.80 | — | — | |
| SCHEMBL24467117 | 0.77 | — | — | |
| SCHEMBL21184293 | 0.76 | — | — | |
| SCHEMBL15214922 | 0.75 | — | — | |
| SCHEMBL22056768 | 0.72 | — | — | |
| SCHEMBL12441619 | 0.72 | — | — | |
| SCHEMBL14684777 | 0.72 | — | — | |
| SCHEMBL14865216 | 0.69 | — | — | |
| SCHEMBL20345188 | 0.69 | — | — | |
| SCHEMBL8063839 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |