Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 9/20 | 0.71 |
| ▸ | BTK | Q06187 | 7/20 | 0.65 |
| ▸ | TXK | P42681 | 4/20 | 0.61 |
| ▸ | NTRK1 | P04629 | 10/20 | 0.57 |
| ▸ | ITK | Q08881 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932944 | 0.93 | JAK3 (0.71) | JAK3BTKTXKNTRK1ITK | |
| SCHEMBL20139064 | 0.93 | JAK3 (0.71) | JAK3BTKTXKNTRK1ITK | |
| SCHEMBL24467287 | 0.89 | JAK3 (0.69) | JAK3BTKTXKNTRK1ITK | |
| SCHEMBL20162010 | 0.87 | JAK3 (0.63) | JAK3BTKTXKNTRK1ITK | |
| SCHEMBL23366094 | 0.85 | JAK3 (0.80) | JAK3BTKTXKNTRK1ITK | |
| SCHEMBL20161915 | 0.85 | JAK3 (0.80) | JAK3BTKTXKNTRK1ITK | |
| SCHEMBL29932937 | 0.83 | JAK3 (1.00) | JAK3BTKTXKITK | |
| SCHEMBL20161437 | 0.83 | JAK3 (1.00) | JAK3BTKTXKITK | |
| SCHEMBL23366056 | 0.83 | JAK3 (0.84) | JAK3BTKTXKNTRK1ITK | |
| SCHEMBL27089741 | 0.83 | JAK3 (0.80) | JAK3BTKTXKNTRK1ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |