Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.79 |
| ▸ | JAK3 | P52333 | 16/20 | 0.79 |
| ▸ | TXK | P42681 | 15/20 | 0.79 |
| ▸ | ITK | Q08881 | 7/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24467288 | 0.97 | JAK3 (0.78) | BTKJAK3TXKITK | |
| SCHEMBL23366069 | 0.91 | BTK (0.77) | BTKJAK3TXKITK | |
| SCHEMBL20161893 | 0.90 | JAK3 (0.85) | BTKJAK3TXKITK | |
| SCHEMBL20161401 | 0.89 | JAK3 (1.00) | BTKJAK3TXKITK | |
| SCHEMBL24467273 | 0.88 | JAK3 (0.80) | BTKJAK3TXKITK | |
| SCHEMBL24467256 | 0.87 | JAK3 (0.84) | BTKJAK3TXKITK | |
| SCHEMBL24467338 | 0.86 | TXK (0.84) | BTKJAK3TXKITK | |
| SCHEMBL20161400 | 0.85 | JAK3 (1.00) | BTKJAK3TXKITK | |
| SCHEMBL20161928 | 0.85 | JAK3 (1.00) | BTKJAK3TXKITK | |
| SCHEMBL24467330 | 0.85 | BTK (0.85) | BTKJAK3TXKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |