Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.80 |
| ▸ | BTK | Q06187 | 17/20 | 0.69 |
| ▸ | TXK | P42681 | 13/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161931 | 0.89 | JAK3 (0.72) | JAK3BTKTXK | |
| SCHEMBL20161480 | 0.89 | JAK3 (1.00) | JAK3BTKTXK | |
| SCHEMBL20161747 | 0.84 | JAK3 (0.77) | JAK3BTKTXK | |
| SCHEMBL20161926 | 0.83 | JAK3 (0.65) | JAK3BTKTXK | |
| SCHEMBL20161556 | 0.82 | JAK3 (1.00) | JAK3BTKTXK | |
| SCHEMBL20161751 | 0.82 | JAK3 (0.66) | JAK3BTKTXK | |
| SCHEMBL20161231 | 0.81 | JAK3 (0.94) | JAK3BTKTXK | |
| SCHEMBL20161955 | 0.81 | JAK3 (0.78) | JAK3BTKTXK | |
| SCHEMBL24467310 | 0.80 | JAK3 (0.83) | JAK3BTKTXK | |
| SCHEMBL20161744 | 0.80 | JAK3 (1.00) | JAK3BTKTXK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |