Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 9/20 | 0.39 |
| ▸ | TXK | P42681 | 9/20 | 0.39 |
| ▸ | ITK | Q08881 | 9/20 | 0.39 |
| ▸ | BTK | Q06187 | 9/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657783 | 0.83 | JAK3 (0.47) | JAK3TXKITKBTK | |
| SCHEMBL29932902 | 0.83 | JAK3 (0.47) | JAK3TXKITKBTK | |
| SCHEMBL20161423 | 0.81 | JAK3 (0.47) | JAK3TXKITKBTK | |
| SCHEMBL24467251 | 0.81 | JAK3 (0.46) | JAK3TXKITKBTK | |
| SCHEMBL29933013 | 0.79 | POLB (0.46) | MYCWDR5NOS1 | |
| SCHEMBL24467153 | 0.77 | JAK3 (0.48) | JAK3TXKITKBTK | |
| SCHEMBL12510000 | 0.77 | HAO1 (0.46) | MYCWDR5 | |
| SCHEMBL14460569 | 0.76 | ITK (0.70) | JAK3TXKITKBTK | |
| SCHEMBL30291400 | 0.76 | ITK (0.70) | JAK3TXKITKBTK | |
| SCHEMBL14460588 | 0.75 | ITK (0.60) | JAK3TXKITKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |
| WO-2018089261-A2 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |