Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL588994 | 0.89 | SYK (1.00) | SYK | |
| SCHEMBL373619 | 0.85 | SYK (0.90) | SYK | |
| SCHEMBL589047 | 0.85 | SYK (1.00) | SYK | |
| SCHEMBL374178 | 0.84 | SYK (1.00) | SYK | |
| SCHEMBL373903 | 0.84 | SYK (0.90) | SYK | |
| SCHEMBL13388674 | 0.83 | SYK (0.96) | SYK | |
| SCHEMBL13406834 | 0.83 | SYK (1.00) | SYK | |
| SCHEMBL373599 | 0.82 | SYK (0.88) | SYK | |
| SCHEMBL373824 | 0.80 | SYK (0.81) | SYK | |
| SCHEMBL13388645 | 0.80 | SYK (1.00) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131582-B1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MEDIATED DISEASES | VERTEX PHARMA (US) | 2018-05-23 | — | — | EP | disclosed |