SCHEMBL2016370

SCHEMBL2016370

O=[N+]([O-])c1csc([N+](=O)[O-])c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.46
CYP19A1 P11511 1/20 0.42
TSHR P16473 3/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 4/20 0.40
NPSR1 Q6W5P4 2/20 0.40
ALDH1A1 P00352 4/20 0.38
PAX8 Q06710 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TXNRD1 Q16881 1/20 0.36
TXNRD3 Q86VQ6 1/20 0.36
TXNRD2 Q9NNW7 1/20 0.36
GAA P10253 1/20 0.36
MAPK1 P28482 1/20 0.36
VCAM1 P19320 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9005006 1.00 PTPRC (0.46) PTPRCCYP19A1TSHRLMNAMAPT
SCHEMBL18430396 0.76
Potassium Ion SCHEMBL8866116 0.74 CYP19A1 (0.41) CYP19A1TSHRLMNANPSR1ALDH1A1
SCHEMBL1457080 0.74
SCHEMBL28808794 0.74
SCHEMBL18499642 0.74
SCHEMBL16290078 0.74
SCHEMBL8463780 0.74
SCHEMBL7915189 0.74 CYP19A1 (0.41) CYP19A1TSHRLMNANPSR1ALDH1A1
SCHEMBL11320926 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516727-B1 DISPERSE AZO DYES COLOURTEX INDUSTRIES LTD (IN) 2018-05-09 EP claimed
CN-102782210-B Disperse azo dyes COLOURTEX IND LTD 2014-07-02 CN claimed
US-8409300-B2 Disperse azo dyes COLOURTEX INDUSTRIES LIMITED (IN) 2013-04-02 US claimed
US-20120291207-A1 DISPERSE AZO DYES COLOURTEX INDUSTRIES LIMITED (IN) 2012-11-22 US claimed
EP-0186252-B1 USE OF THIOPHENE COMPOUNDS FOR THE MANUFACTURE OF A MEDICAMENT AGAINST TUMOURS CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1992-04-01 EP claimed
EP-0047079-B1 NONAPEPTIDES AFFECTING GONADAL FUNCTION THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1984-02-22 EP claimed
US-4382922-A Peptides affecting gonadal function THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1983-05-10 US claimed
EP-0021620-B1 WATER-SOLUBLE PEPTIDES AFFECTING GONADAL FUNCTION THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1983-02-23 EP claimed
US-4244946-A LUTEINIZING-HORMONE RELEASING FACTOR AGONISTS AS ANTIFERTILITY AGENTS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1981-01-13 US claimed
EP-0021620-A1 Water-soluble peptides affecting gonadal function THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1981-01-07 EP claimed
US-3971737-A [2-Methyl-Ala6 ]LRH AMERICAN HOME PRODUCTS CORPORATION (US) 1976-07-27 US claimed
CN-113748216-B Single-channel sequencing method based on self-luminescence 青岛华大智造科技有限责任公司 2024-04-23 CN disclosed
CN-114286867-B Method for sequencing polynucleotide based on luminous marker optical signal dynamics and secondary luminous signal 青岛华大智造科技有限责任公司 2024-04-16 CN disclosed
CN-112840035-B Method for sequencing polynucleotides 青岛华大智造科技有限责任公司 2024-01-30 CN disclosed
CN-110563630-B Organic compound based on cyanine and application thereof 滨州医学院 2023-01-17 CN disclosed
EP-0047079-A1 Nonapeptides affecting gonadal function THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1982-03-10 EP disclosed
EP-0039054-A1 Water-insoluble azo dyes, process for their production and their application CASSELLA Aktiengesellschaft (DE) 1981-11-04 EP disclosed
US-4244946-A LUTEINIZING-HORMONE RELEASING FACTOR AGONISTS AS ANTIFERTILITY AGENTS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1981-01-13 US disclosed
EP-0021620-A1 Water-soluble peptides affecting gonadal function THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1981-01-07 EP disclosed
US-3971737-A [2-Methyl-Ala6 ]LRH AMERICAN HOME PRODUCTS CORPORATION (US) 1976-07-27 US disclosed