Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14677239 | 0.90 | POLB (0.52) | POLBALDH1A1KDM4EDDR1MEN1 | |
| SCHEMBL29431598 | 0.90 | POLB (0.52) | POLBALDH1A1KDM4EDDR1MEN1 | |
| SCHEMBL25887368 | 0.90 | POLB (0.42) | POLBGRIN1GRIN2BCHRNB1CHRNB2 | |
| SCHEMBL30989696 | 0.90 | POLB (0.42) | POLBGRIN1GRIN2BCHRNB1CHRNB2 | |
| SCHEMBL17688765 | 0.87 | KDM4E (0.34) | POLBGRIN1GRIN2BTP53GAA | |
| SCHEMBL15868302 | 0.86 | POLB (0.48) | POLBALDH1A1MEN1NPC1STAT3 | |
| SCHEMBL23971584 | 0.85 | POLB (0.50) | POLBALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL17986660 | 0.85 | POLB (0.48) | POLBALDH1A1MEN1NPC1STAT3 | |
| SCHEMBL23729027 | 0.85 | POLB (0.48) | POLBALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL14684609 | 0.85 | POLB (0.48) | POLBALDH1A1MEN1NPC1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-24 | — | — | WO | disclosed |
| WO-2018091389-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-24 | — | — | WO | disclosed |