SCHEMBL20165811

SCHEMBL20165811

COc1c(C(C)(C)C)cc2c(c1-c1cc(C)cc(C)c1)C=C(CC(C)(C)C)C2[Zr](Cl)(Cl)(C1C(CC(C)(C)C)=Cc2c1cc(C(C)(C)C)c(OC)c2-c1cc(C)cc(C)c1)[SiH](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20165773 0.89
Hydrochloric Acid SCHEMBL21433891 0.84
SCHEMBL28350544 0.83
SCHEMBL20165708 0.79
SCHEMBL29873763 0.79
SCHEMBL21451187 0.79
SCHEMBL20165767 0.79
SCHEMBL20350493 0.79
SCHEMBL27076792 0.78
SCHEMBL2595789 0.77 PDE4A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110177798-B Catalyst and process for preparing same 博里利斯股份公司 2022-08-30 CN disclosed
US-11352376-B2 Catalysts BOREALIS AG (AT) 2022-06-07 US disclosed
EP-3541823-B1 CATALYSTS BOREALIS AG (AT) 2020-12-30 EP disclosed
US-20190308995-A1 CATALYSTS BOREALIS AG (AT) 2019-10-10 US disclosed
EP-3541823-A1 CATALYSTS Borealis AG (AT) 2019-09-25 EP disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed