Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28482596 | 0.92 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1CTDSP1TSHRMAPT | |
| SCHEMBL21522949 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1CTDSP1TSHRMAPT | |
| SCHEMBL20165461 | 0.82 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1CTDSP1TSHRMAPT | |
| SCHEMBL27341985 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1CTDSP1TSHRMAPT | |
| SCHEMBL20166020 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1CTDSP1TSHRMAPT | |
| SCHEMBL20165410 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1CTDSP1TSHRMAPT | |
| SCHEMBL21522835 | 0.78 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1CTDSP1TSHRMAPT | |
| SCHEMBL28488970 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1CTDSP1TSHRMAPT | |
| SCHEMBL21522882 | 0.77 | MAPT (0.44) | SMN1; SMN2ALDH1A1CTDSP1TSHRMAPT | |
| SCHEMBL20168873 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1CTDSP1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541857-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2020-09-09 | — | — | EP | disclosed |
| US-10654946-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2020-05-19 | — | — | US | disclosed |
| US-20190330388-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-10-31 | — | — | US | disclosed |
| EP-3541857-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018091375-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-05-24 | — | — | WO | disclosed |