Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2381366 | 1.00 | CYP19A1 (0.59) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL989344 | 0.81 | CYP19A1 (0.47) | CYP19A1MAOBPKMTSHR | |
| SCHEMBL6592452 | 0.81 | CYP19A1 (0.59) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| Hydrochloric Acid SCHEMBL697520 | 0.79 | CYP19A1 (0.57) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL18415628 | 0.78 | CYP19A1 (0.61) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL16110707 | 0.78 | CYP19A1 (0.48) | CYP19A1 | |
| SCHEMBL9094361 | 0.78 | CYP19A1 (0.56) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL7241604 | 0.77 | CYP19A1 (0.59) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL768947 | 0.77 | CYP19A1 (0.59) | CYP19A1MAOBPKMTSHRSIGMAR1 | |
| SCHEMBL15147097 | 0.77 | CYP19A1 (0.59) | CYP19A1MAOBPKMTSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541812-A1 | MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS | Takeda Pharmaceutical Company Limited (JP) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018092921-A1 | MGLUR7 AGONIST COMPOUNDS FOR TREATING MGLUR7- REGULATED DISEASES, DISORDERS, OR CONDITIONS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-05-24 | — | — | WO | disclosed |