Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18549091 | 1.00 | TOP2A (0.35) | TOP2A | |
| SCHEMBL19464443 | 0.86 | TOP2A (0.37) | TOP2A | |
| SCHEMBL16777627 | 0.86 | TOP2A (0.37) | TOP2A | |
| SCHEMBL17215151 | 0.84 | TOP2A (0.35) | TOP2A | |
| SCHEMBL20789104 | 0.84 | TOP2A (0.35) | TOP2A | |
| SCHEMBL18817574 | 0.84 | TOP2A (0.35) | TOP2A | |
| SCHEMBL16777798 | 0.84 | TOP2A (0.35) | TOP2A | |
| SCHEMBL18817224 | 0.84 | TOP2A (0.35) | TOP2A | |
| SCHEMBL18815510 | 0.84 | TOP2A (0.35) | TOP2A | |
| SCHEMBL14028075 | 0.81 | TOP2A (0.37) | TOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093717-A1 | COMPOSITIONS AND METHODS FOR TREATING HCV INFECTION | ABBVIE INC. (US) | 2018-05-24 | — | — | WO | disclosed |