Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19366702 | 0.85 | NT5E (0.73) | NT5E | |
| SCHEMBL23915097 | 0.85 | NT5E (0.73) | NT5E | |
| SCHEMBL24618960 | 0.83 | NT5E (0.70) | NT5E | |
| SCHEMBL27210210 | 0.79 | NT5E (0.73) | NT5E | |
| SCHEMBL24672753 | 0.79 | NT5E (0.76) | NT5E | |
| SCHEMBL19366711 | 0.79 | NT5E (0.71) | NT5E | |
| SCHEMBL22614572 | 0.79 | NT5E (1.00) | NT5E | |
| SCHEMBL23915018 | 0.78 | NT5E (1.00) | NT5E | |
| SCHEMBL21839576 | 0.78 | NT5E (0.80) | NT5E | |
| SCHEMBL20524201 | 0.78 | NT5E (1.00) | NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541396-A1 | INHIBITORS OF CD73-MEDIATED IMMUNOSUPPRESSION | Arcus Biosciences, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018094148-A1 | INHIBITORS OF CD73-MEDIATED IMMUNOSUPPRESSION | ARCUS BIOSCIENCES, INC. (US) | 2018-05-24 | — | — | WO | disclosed |