Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13762421 | 0.98 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28909848 | 0.98 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13788303 | 0.98 | TSHR (0.76) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL31581001 | 0.94 | TSHR (0.68) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL22710565 | 0.88 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL244114 | 0.87 | TSHR (0.95) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL12547083 | 0.85 | TSHR (0.60) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9101988 | 0.84 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13945622 | 0.84 | TSHR (1.00) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| Ethylene SCHEMBL977945 | 0.84 | TSHR (0.90) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9976087-B2 | Liquid crystal composition and liquid crystal optical device | ASAHI GLASS COMPANY, LIMITED (JP) | 2018-05-22 | — | — | US | disclosed |