Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.55 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.55 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | P2RY10 | O00398 | 5/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecylamine SCHEMBL28985670 | 0.96 | LPAR3 (0.60) | LPAR3LPAR2LPAR1PLA2G2CCYP3A4 | |
| Hexadecylamine SCHEMBL28985683 | 0.96 | LPAR3 (0.60) | LPAR3LPAR2LPAR1PLA2G2CCYP3A4 | |
| Dodecylamine SCHEMBL27830349 | 0.96 | LPAR3 (0.60) | LPAR3LPAR2LPAR1PLA2G2CCYP3A4 | |
| SCHEMBL9301085 | 0.94 | LPAR3 (0.62) | LPAR3LPAR2LPAR1PLA2G2CDNM1 | |
| SCHEMBL10885700 | 0.94 | LPAR3 (0.62) | LPAR3LPAR2LPAR1PLA2G2CDNM1 | |
| Dodecylamine SCHEMBL9495208 | 0.94 | LPAR3 (0.62) | LPAR3LPAR2LPAR1PLA2G2CDNM1 | |
| Dodecylamine SCHEMBL10887166 | 0.94 | LPAR3 (0.62) | LPAR3LPAR2LPAR1PLA2G2CDNM1 | |
| SCHEMBL22221628 | 0.94 | LPAR3 (0.62) | LPAR3LPAR2LPAR1PLA2G2CDNM1 | |
| SCHEMBL9499065 | 0.94 | LPAR3 (0.57) | LPAR3LPAR2LPAR1PLA2G2CCYP3A4 | |
| Dodecylamine SCHEMBL17472938 | 0.94 | LPAR3 (0.62) | LPAR3LPAR2LPAR1PLA2G2CDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9976147-B2 | STAT3 inhibitors and uses thereof | CITY OF HOPE (US) | 2018-05-22 | — | — | US | disclosed |
| US-9976147-B2 | STAT3 inhibitors and uses thereof | CITY OF HOPE (US) | 2018-05-22 | — | — | US | disclosed |