Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 1.00 |
| ▸ | TEC | P42680 | 10/20 | 0.83 |
| ▸ | TXK | P42681 | 10/20 | 0.83 |
| ▸ | BMX | P51813 | 10/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18996791 | 1.00 | BTK (1.00) | BTKTECTXKBMX | |
| SCHEMBL18996800 | 0.93 | BTK (1.00) | BTKTECTXKBMX | |
| SCHEMBL18996801 | 0.93 | BTK (1.00) | BTKTECTXKBMX | |
| SCHEMBL18996811 | 0.91 | BTK (1.00) | BTKTECTXKBMX | |
| SCHEMBL20169160 | 0.91 | BTK (1.00) | BTKTECTXKBMX | |
| SCHEMBL18996784 | 0.91 | BTK (1.00) | BTKTECTXKBMX | |
| SCHEMBL18996933 | 0.89 | BTK (0.80) | BTKTECTXKBMX | |
| SCHEMBL18996798 | 0.89 | BTK (1.00) | BTKTECTXKBMX | |
| SCHEMBL18996809 | 0.89 | BTK (1.00) | BTKTECTXKBMX | |
| SCHEMBL18996792 | 0.88 | BTK (1.00) | BTKTECTXKBMX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975882-B2 | Heteroaromatic compounds as BTK inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-05-22 | — | — | US | disclosed |
| US-9975882-B2 | Heteroaromatic compounds as BTK inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-05-22 | — | — | US | disclosed |