SCHEMBL20169301

SCHEMBL20169301

Cc1ccc(-c2cccs2)cc1C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.51
KCNH2 Q12809 1/20 0.47
S1PR1 P21453 2/20 0.44
ALDH1A1 P00352 3/20 0.44
GAA P10253 2/20 0.44
NOTUM Q6P988 1/20 0.42
PDK2 Q15119 1/20 0.42
CCNE2 O96020 1/20 0.42
CDK4 P11802 1/20 0.42
CCND1 P24385 1/20 0.42
CCNE1 P24864 1/20 0.42
CDK2 P24941 1/20 0.42
PGR P06401 1/20 0.41
LTA4H P09960 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PRMT6 Q96LA8 1/20 0.41
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
OPRK1 P41145 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20169308 0.86 ERN1 (0.48) ERN1KCNH2ALDH1A1GAAPDK2
SCHEMBL9335104 0.80 KCNH2 (0.55) ERN1KCNH2ALDH1A1NOTUMPGR
SCHEMBL28222643 0.79 ERN1 (0.51) ERN1KCNH2PDK2CCNE2CDK4
SCHEMBL2368386 0.79 ERN1 (0.51) ERN1KCNH2NOTUMPDK2LTA4H
SCHEMBL30742957 0.79 NOTUM (0.53) S1PR1NOTUMPGR
SCHEMBL5949403 0.79 NOTUM (0.53) S1PR1NOTUMPGR
SCHEMBL30742956 0.79 NOTUM (0.53) S1PR1NOTUMPGR
SCHEMBL27870963 0.79 KCNH2 (0.50) ERN1KCNH2ALDH1A1PGRLTA4H
SCHEMBL5949422 0.77 AR (0.52) S1PR1NOTUMPGR
SCHEMBL16596476 0.76 ERN1 (0.48) ERN1KCNH2PDK2CCNE2CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3048107-B1 BENZOBIS (THIADIAZOLE) DERIVATIVE, INK CONTAINING SAME, AND ORGANIC ELECTRONIC DEVICE USING SAME FUTURE INK CORP (JP) 2021-01-13 EP disclosed
US-9978954-B2 Benzobis (thiadiazole) derivative, ink comprising same, and organic electronic device comprising same UBE INDUSTRIES, LTD. (JP) 2018-05-22 US disclosed