Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 6/20 | 0.45 |
| ▸ | RBBP4 | Q09028 | 6/20 | 0.45 |
| ▸ | SUZ12 | Q15022 | 6/20 | 0.45 |
| ▸ | AEBP2 | Q6ZN18 | 5/20 | 0.45 |
| ▸ | EZH2 | Q15910 | 17/20 | 0.45 |
| ▸ | RBBP7 | Q16576 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19391478 | 0.92 | EZH2 (0.46) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391666 | 0.90 | EED (0.45) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391678 | 0.89 | EED (0.47) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL20170094 | 0.89 | EED (0.45) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391698 | 0.88 | EZH2 (0.45) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391347 | 0.87 | EZH2 (0.56) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391636 | 0.87 | EZH2 (0.46) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391397 | 0.86 | EED (0.46) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391677 | 0.86 | EZH2 (0.57) | EEDRBBP4SUZ12AEBP2EZH2 | |
| SCHEMBL19391475 | 0.86 | EED (0.48) | EEDRBBP4SUZ12AEBP2EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323820-A1 | SUBSTITUTED 6,5-FUSED BICYCLIC HETEROARYL COMPOUNDS | Epizyme, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |