Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19020687 | 0.85 | EPHX1 (0.44) | EPHX1KDM4AKDM4CPAOXADRA1A | |
| SCHEMBL19724804 | 0.75 | EPHX1 (0.39) | EPHX1KDM4AKDM4CPAOXADRA1A | |
| SCHEMBL12640843 | 0.75 | — | — | |
| SCHEMBL16084907 | 0.75 | — | — | |
| SCHEMBL20733123 | 0.75 | EPHX1 (0.35) | EPHX1KDM4AKDM4CSIGMAR1 | |
| SCHEMBL20044923 | 0.73 | EPHX1 (0.38) | EPHX1KDM4AKDM4CPAOXADRA1A | |
| SCHEMBL22679356 | 0.73 | PAOX (0.33) | EPHX1KDM4AKDM4CPAOX | |
| SCHEMBL24812346 | 0.73 | PAOX (0.57) | EPHX1KDM4AKDM4CPAOXADRA1A | |
| SCHEMBL22954504 | 0.73 | PAOX (0.57) | EPHX1KDM4AKDM4CPAOXADRA1A | |
| SCHEMBL18932735 | 0.73 | PAOX (0.57) | EPHX1KDM4AKDM4CPAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970334-B1 | MACROCYCLIC COMPOUNDS AS IRAK4 INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES | BIOGEN MA INC (US) | 2018-05-23 | — | — | EP | disclosed |