Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19775410 | 0.85 | PTPRB (0.74) | PTPRB | |
| SCHEMBL3610945 | 0.84 | PTPRB (1.00) | PTPRB | |
| SCHEMBL684268 | 0.84 | PTPRB (1.00) | PTPRB | |
| SCHEMBL5122747 | 0.82 | PTPRB (0.69) | PTPRB | |
| SCHEMBL5773296 | 0.82 | PTPRB (0.69) | PTPRB | |
| SCHEMBL24052389 | 0.80 | PTPRB (0.75) | PTPRB | |
| SCHEMBL14051421 | 0.80 | PTPRB (0.66) | PTPRB | |
| SCHEMBL8587261 | 0.75 | PTPRB (0.42) | PTPRB | |
| SCHEMBL24308822 | 0.74 | PTPRB (0.81) | PTPRB | |
| SCHEMBL24308697 | 0.73 | PTPRB (0.79) | PTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323815-A1 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | Aerpio Therapeutics, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |