Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CHAT | P28329 | 1/20 | 0.47 |
| ▸ | QDPR | P09417 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13852005 | 0.77 | KMT2A (0.51) | KMT2ANPC1RAB9AALDH1A1CHAT | |
| SCHEMBL13229286 | 0.73 | KMT2A (0.48) | KMT2ANPC1RAB9AALDH1A1CHAT | |
| SCHEMBL2194891 | 0.72 | — | — | |
| SCHEMBL11792652 | 0.71 | KMT2A (0.80) | KMT2ANPC1RAB9AALDH1A1CHAT | |
| SCHEMBL11792658 | 0.71 | KMT2A (0.80) | KMT2ANPC1RAB9AALDH1A1CHAT | |
| Hydrochloric Acid SCHEMBL11789369 | 0.70 | KMT2A (0.83) | KMT2ANPC1RAB9AALDH1A1CHAT | |
| Hydrochloric Acid SCHEMBL11789363 | 0.70 | KMT2A (0.83) | KMT2ANPC1RAB9AALDH1A1CHAT | |
| SCHEMBL10261965 | 0.69 | KMT2A (0.67) | KMT2ANPC1RAB9AALDH1A1CHAT | |
| SCHEMBL9499887 | 0.68 | KMT2A (0.43) | KMT2ANPC1RAB9AALDH1A1CHAT | |
| SCHEMBL11792003 | 0.67 | CHAT (0.64) | KMT2ANPC1RAB9AALDH1A1CHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-B1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2018-05-23 | — | — | EP | disclosed |