Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 5/20 | 0.33 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | PPP5C | P53041 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16607300 | 0.86 | PLG (0.38) | PLGPLATLMNAGRM2GRM3 | |
| SCHEMBL2816981 | 0.85 | PLG (0.40) | PLGPLATLMNAGRM2GRM3 | |
| SCHEMBL18913137 | 0.83 | GRM2 (0.36) | PLGPLATLMNAGRM2GRM3 | |
| SCHEMBL29282868 | 0.83 | PLG (0.39) | PLGPLATLMNAGRM2GRM3 | |
| SCHEMBL29282870 | 0.83 | PLG (0.39) | PLGPLATLMNAGRM2GRM3 | |
| SCHEMBL29282898 | 0.83 | PLG (0.39) | PLGPLATLMNAGRM2GRM3 | |
| SCHEMBL30922239 | 0.83 | PLG (0.39) | PLGPLATLMNAGRM2GRM3 | |
| SCHEMBL11846223 | 0.78 | GABRR1 (0.42) | PLGPLATLMNAGRM2GRM3 | |
| SCHEMBL12165165 | 0.78 | PPM1B (0.39) | — | |
| SCHEMBL14186720 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068782-B1 | METHODS OF PREPARING INHIBITORS OF INFLUENZA VIRUSES REPLICATION | VERTEX PHARMA (US) | 2018-05-23 | — | — | EP | disclosed |