Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.75 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171922 | 0.91 | CNR2 (0.75) | CNR2CNR1 | |
| SCHEMBL20171879 | 0.87 | CNR2 (0.76) | CNR2CNR1 | |
| SCHEMBL16212116 | 0.86 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL16211671 | 0.83 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL16212064 | 0.83 | CNR2 (1.00) | CNR2 | |
| SCHEMBL16212061 | 0.83 | CNR2 (1.00) | CNR2 | |
| SCHEMBL20171936 | 0.83 | CNR2 (0.76) | CNR2CNR1PIK3CAPIK3CBPIK3CG | |
| SCHEMBL16211990 | 0.83 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL20171847 | 0.78 | CNR2 (0.77) | CNR2CNR1 | |
| SCHEMBL20171907 | 0.78 | CNR2 (0.75) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991987-B1 | PURINE DERIVATIVES AS CB2 RECEPTOR AGONISTS | HOFFMANN LA ROCHE (CH) | 2018-05-23 | — | — | EP | disclosed |