Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18806020 | 0.89 | ELANE (0.43) | ELANEKMT2AATMSMN1; SMN2HSD17B10 | |
| SCHEMBL23255224 | 0.86 | ELANE (0.43) | ELANEKMT2AATMHSD17B10ACACB | |
| SCHEMBL25570168 | 0.86 | ELANE (0.41) | ELANEKMT2AATMHSD17B10ACACB | |
| SCHEMBL21231952 | 0.85 | ELANE (0.40) | ELANEKMT2AATMHSD17B10MAPT | |
| SCHEMBL20172068 | 0.84 | AKR1C3 (0.39) | ELANEKMT2AATMALOX5MAPT | |
| SCHEMBL18808040 | 0.83 | ELANE (0.46) | ELANEKMT2AATMHSD17B10ACACB | |
| SCHEMBL18806039 | 0.83 | ELANE (0.41) | ELANEKMT2AATMMAPTACACB | |
| SCHEMBL18806033 | 0.83 | ELANE (0.39) | ELANEKMT2AATMHSD17B10ACACB | |
| SCHEMBL18806035 | 0.82 | ELANE (0.38) | ELANEKMT2AATMHSD17B10MAPT | |
| SCHEMBL21231953 | 0.81 | MAPT (0.42) | KMT2ASMN1; SMN2ALOX5MAPTACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162875-B1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2018-05-23 | — | — | EP | disclosed |