Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | CTSG | P08311 | 3/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13258320 | 0.95 | KCNH2 (0.46) | KCNH2KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL87415 | 0.80 | ELANE (0.44) | KCNH2KDM4EALDH1A1TDP1ELANE | |
| SCHEMBL10373980 | 0.75 | KCNH2 (0.74) | KCNH2TDP1SMN1; SMN2TLR8NOS2 | |
| SCHEMBL9971347 | 0.73 | KCNH2 (0.78) | KCNH2SMN1; SMN2 | |
| SCHEMBL22299298 | 0.73 | KCNH2 (0.78) | KCNH2SMN1; SMN2 | |
| SCHEMBL16228294 | 0.73 | KCNH2 (0.78) | KCNH2SMN1; SMN2 | |
| SCHEMBL16228298 | 0.73 | KCNH2 (0.78) | KCNH2SMN1; SMN2 | |
| SCHEMBL16227752 | 0.73 | KCNH2 (0.78) | KCNH2SMN1; SMN2 | |
| SCHEMBL26162438 | 0.73 | KCNH2 (0.78) | KCNH2SMN1; SMN2 | |
| SCHEMBL681574 | 0.73 | KCNH2 (0.64) | KCNH2GRM5SMN1; SMN2HSD17B3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2396801-B1 | OLED DEVICE WITH FLUORANTHENE-MACROCYCLIC MATERIALS | GLOBAL OLED TECHNOLOGY LLC (US) | 2018-05-23 | — | — | EP | disclosed |